Needle-free device used in the skin cancer vaccine trial

Skin Cancer Vaccine Trial Fast-Tracked by NHS

The NHS is fast-tracking a skin cancer vaccine trial for patients with advanced melanoma in England. This breakthrough vaccine aims to improve survival and reduce the chances of cancer returning.

What Is the Skin Cancer Vaccine Trial?

The trial tests a new DNA-based vaccine called iSCIB1+, developed by Scancell. It teaches the immune system to recognize and attack melanoma cells. Unlike traditional shots, this vaccine is delivered needle-free using a quick, high-pressure spray under the skin.

It targets specific markers found on cancer cells. As a result, the immune system learns to attack these cells and “remember” them in case the cancer returns.

According to the NHS Cancer Vaccine Launch Pad, this approach is part of a broader effort to bring more personalized cancer treatments to patients faster.

Inside the NHS Cancer Vaccine Trial: The SCOPE Study

This skin cancer vaccine trial is part of the SCOPE study, which is being led by the Southampton Clinical Trials Unit. The study is now in phase two and will continue to recruit patients through October 2025. It’s one of several trials under the NHS Cancer Vaccine Launch Pad, which is helping patients access cutting-edge treatments sooner.

To qualify, patients take a blood test to check their immune compatibility with the vaccine. This personalized match helps the treatment work better and limits side effects.

Real Results from the Vaccine Trial

Paul Thomas, 63, from Hampshire, was one of the first to join the skin cancer vaccine trial. He shared, “I feel lucky to be on the trial. Since I started, my tumors have shrunk. Every scan shows more improvement. It’s really exciting.”

Stories like Paul’s offer real hope. For people with few remaining treatment options, this vaccine could make a meaningful difference.

Why Personalized Cancer Vaccines Matter

The NHS plans to enroll up to 10,000 people in cancer vaccine trials by 2030. Furthermore, it is working with biotech companies to expand access to customized cancer therapies.

Prime Minister Keir Starmer praised the effort, saying, “This kind of innovation is vital. We want more people to benefit from life-changing treatments like this.”

To learn more about skin cancer, visit the NHS melanoma cancer guide.


Medical Disclaimer: This article is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or specialist regarding any medical concerns or options.

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